WebBackground/aims: Argatroban, a hepatically metabolized direct thrombin inhibitor, is approved for use in heparin-induced thrombocytopenia (HIT; several countries) and in antithrombin-deficient patients undergoing hemodialysis (Japan). This literature analysis aimed to determine the effects of renal function on argatroban pharmacokinetics, … Web25 ott 2024 · Anticoagulation was maintained with argatroban and monitored based on activated clotting time (ACT) and aPTT, with target levels of 160–180 s and 50–70 s, respectively. Intraoperative argatroban doses ranged between 0.4 and 0.6 μg/kg/min, resulting in ACT of 162–207 s and aPTT of 45–75 s (Fig. 2).
Treatment of pulmonary embolism with argatroban and …
WebArgatroban should not be mixed with other drugs prior to dilution. Dilution is not required for Argatroban Injection 50 mg/50 mL (1 mg/mL). Argatroban Injection 250 mg/2.5 mL (100 mg/mL) Argatroban 250 mg/2.5 mL (100 mg/mL) should be diluted in 0.9% Sodium Chloride Injection, 5% Dextrose WebBased on the results of first prospective clinical studies, the recommended starting dose of argatroban for treatment of acute HIT was 2 µg · kg –1 · min –1. 39 However, more recent studies showed that patients with … simulation montant de la retraite
Argatroban: Package Insert - Drugs.com
Web8 feb 2024 · The guideline panel identified all-cause mortality, pulmonary embolism (PE), deep vein thrombosis ... VTE, should we use direct oral anticoagulants, low-molecular-weight heparin, unfractionated heparin, fondaparinux, argatroban, or bivalirudin at ... and recommends against intensification of anticoagulant dosing based on D ... Web22 ago 2024 · Argatroban Dosage Usual Adult Dose for Thrombotic/Thromboembolic Disorder. Initial: 2 mcg/kg/min administered as a constant infusion. Usual Pediatric Dose … Web24 lug 2012 · In patients with a history of heparin-induced thrombocytopenia, heparin products should be avoided. Alternatives include short-acting direct thrombin inhibitor therapy such as argatroban, … paul\u0027s unique choice